ACY1 Polyclonal Antibody

This gene encodes a cytosolic| homodimeric| zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group| and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1| a region reduced to homozygosity in small-cell lung cancer (SCLC)| and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart| and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als

The ACY1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of ACY1 protein in various biological samples. This antibody has been extensively validated for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

The ACY1 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results. It recognizes the ACY1 protein with high affinity, enabling the detection of even low levels of ACY1 expression. This antibody has been rigorously tested against a wide range of species, including human, mouse, and rat, ensuring its versatility and applicability across different research areas.

With its polyclonal nature, this antibody offers several advantages over monoclonal antibodies. It recognizes multiple epitopes on the ACY1 protein, enhancing the chances of successful detection and reducing the risk of false negatives. Additionally, the ACY1 Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, further enhancing its specificity.

The ACY1 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. This antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability.

In summary, the ACY1 Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of ACY1 protein. Its exceptional sensitivity, specificity, and versatility make it an ideal choice for researchers in various fields, including molecular biology, biochemistry, and cell biology.