ADAMTS-12 Polyclonal Antibody

ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by ADAMTS12 contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

The ADAMTS-12 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of ADAMTS-12 protein in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards ADAMTS-12.

ADAMTS-12, a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family, plays a crucial role in extracellular matrix remodeling and tissue homeostasis. It is involved in various physiological and pathological processes, including development, wound healing, and arthritis.

The ADAMTS-12 Polyclonal Antibody exhibits exceptional sensitivity and selectivity, making it an ideal tool for researchers and scientists working in the fields of molecular biology, biochemistry, and immunology. It enables the accurate detection and quantification of ADAMTS-12 protein levels, facilitating a deeper understanding of its biological functions and potential implications in disease mechanisms.

This antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested on a wide range of sample types, ensuring reliable and reproducible results.

With its superior performance and reliability, the ADAMTS-12 Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying ADAMTS-12-mediated processes.