ADCK2 Polyclonal Antibody

ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.

The ADCK2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ADCK2 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity.

The ADCK2 Polyclonal Antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the ADCK2 protein. The resulting antibody is purified using a combination of affinity chromatography and protein A/G purification methods, ensuring high purity and minimal cross-reactivity.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the ADCK2 protein in a variety of cell lines and tissues, making it an ideal choice for researchers studying ADCK2-related pathways and diseases.

The ADCK2 Polyclonal Antibody offers numerous advantages over other commercially available antibodies. Its high specificity and sensitivity enable accurate and reliable detection of ADCK2 protein expression, even at low levels. Additionally, its versatility allows for its use in multiple experimental techniques, providing researchers with flexibility and convenience.

In summary, the ADCK2 Polyclonal Antibody is a valuable tool for researchers investigating the role of ADCK2 protein in various biological processes. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset in the field of molecular biology and biomedical research.