Adducin  Alpha/Beta Polyclonal Antibody

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca (2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

The Adducin Alpha/Beta Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The Adducin Alpha/Beta Polyclonal Antibody is designed to detect both alpha and beta adducin isoforms, making it an ideal tool for studying the expression and function of these proteins in various biological systems.

This antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in a range of sample types, including tissue lysates, cell lysates, and purified proteins. The Adducin Alpha/Beta Polyclonal Antibody is also compatible with a range of detection methods, including chemiluminescence and fluorescence.

The Adducin Alpha/Beta Polyclonal Antibody is manufactured to the highest standards of quality and purity, ensuring consistent and reliable results. It is supplied in a convenient format, with a range of sizes available to suit your specific needs. This antibody is an essential tool for researchers studying the role of adducin isoforms in various biological processes, including cell adhesion, cytoskeletal organization, and signal transduction.