ADK Polyclonal Antibody

ADK an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

The ADK Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of adenosine kinase (ADK) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ADK protein, followed by affinity purification using a column containing the same peptide. The resulting antibody exhibits high affinity and specificity towards ADK protein, with minimal cross-reactivity to other proteins.

The ADK Polyclonal Antibody is suitable for a wide range of applications, including western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous ADK protein in various tissues and cell lines. This antibody is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative, and is available in various sizes to meet the needs of different experimental setups.

Overall, the ADK Polyclonal Antibody is a reliable and effective tool for studying ADK protein expression and function in biological systems. Its high specificity and sensitivity make it a valuable asset for researchers in the fields of neuroscience, metabolism, and cancer biology, among others.