Adrenocorticotropin(ACTH) Polyclonal Antibody

This gene encodes a preproprotein that undergoes extensive| tissue-specific| post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and| depending on tissue type and the available convertases| processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin| essential for normal steroidogenesis and the maintenance of normal adrenal weight| and lipotropin beta are the major end products. In other tissues| including the hypothalamus| placenta| and epithelium| all cleavage sites may be used| giving rise to peptides with roles in pain and energy homeostasis| melanocyte stimulation| and immune modulation. The

The Adrenocorticotropin (ACTH) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of ACTH in various biological samples. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the ACTH protein.

With its exceptional affinity and selectivity, this polyclonal antibody enables accurate and reliable measurement of ACTH levels in research and clinical settings. It exhibits minimal cross-reactivity with other related peptides, ensuring precise and specific results.

The ACTH Polyclonal Antibody is suitable for various applications, including enzyme-linked immunosorbent assays (ELISA), immunohistochemistry (IHC), and western blotting. Its versatility allows for the detection of ACTH in different sample types, such as serum, plasma, tissue lysates, and cell culture supernatants.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing waste. The product is stored at recommended temperatures to maintain its stability and functionality.

In summary, the ACTH Polyclonal Antibody is a valuable tool for researchers and clinicians involved in the study and diagnosis of ACTH-related disorders. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory or clinical setting requiring accurate ACTH detection and quantification.