AFP Polyclonal Antibody

AFP encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. Alpha-fetoprotein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

The AFP Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of Alpha-fetoprotein (AFP) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the AFP protein. It has been extensively validated for its specificity and affinity towards AFP, ensuring accurate and reliable results.

The AFP Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including enzyme-linked immunosorbent assays (ELISA), Western blotting, immunohistochemistry, and flow cytometry. Its versatility allows for the detection of AFP in serum, plasma, tissue lysates, and cell culture supernatants, making it an invaluable tool for researchers and clinicians alike.

With its high sensitivity, the AFP Polyclonal Antibody can detect AFP at low concentrations, enabling the detection of early-stage cancers and monitoring of therapeutic interventions. Its robustness and reproducibility ensure consistent results across experiments, facilitating reliable data interpretation and analysis.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, allowing for multiple experiments without the need for frequent reordering. The AFP Polyclonal Antibody is manufactured under strict quality control measures, ensuring batch-to-batch consistency and reliability.

In summary, the AFP Polyclonal Antibody is a superior immunological tool for the accurate detection and quantification of AFP. Its high specificity, sensitivity, and versatility make it an essential component in cancer research, diagnostics, and therapeutic monitoring.