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ELK Biotechnology
SKU(재고 관리 코드):ES9368
AGRIN Rabbit Polyclonal Antibody
AGRIN Rabbit Polyclonal Antibody
AGRIN Rabbit Polyclonal Antibody
Overview
| Product name: | AGRIN rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 1900-1980 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 224kD |
| GeneID（Human）: | 375790 |
| Human Swiss-Prot No: | O00468 |
| Cellular localization: | [Isoform 1]: Secreted, extracellular space, extracellular matrix . Synaptic basal lamina at the neuromuscular junction. .; [Isoform 2]: Cell junction, synapse . Cell membrane ; Single-pass type II membrane protein . |
| Background: | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015], |
| Species Reactivity: | Human;Mouse;Rat |
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