AIP4 Polyclonal Antibody

ITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in ITCH are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH.

The AIP4 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using a polyclonal approach, which ensures a high degree of specificity and sensitivity. The AIP4 Polyclonal Antibody is designed to recognize and bind to the AIP4 protein, which is a member of the Nedd4 family of E3 ubiquitin ligases. This protein is involved in the regulation of various cellular processes, including endocytosis, protein trafficking, and signal transduction.

The AIP4 Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is supplied in a convenient format, with a concentration of 1 mg/ml, and is available in various sizes to meet the needs of different research projects. The AIP4 Polyclonal Antibody is a reliable and effective tool for researchers studying the function and regulation of the AIP4 protein in various cellular processes.