AIRE-1 Polyclonal Antibody

AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

The AIRE-1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Autoimmune Regulator (AIRE) protein expression. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that recognize multiple epitopes on the AIRE protein.

The AIRE-1 Polyclonal Antibody has been rigorously validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reproducible results in both research and diagnostic settings.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and optimal performance. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

The AIRE-1 Polyclonal Antibody is designed to provide researchers and clinicians with a reliable tool for studying the role of AIRE protein in autoimmune diseases and related disorders. Its high affinity and selectivity make it an ideal choice for investigating AIRE expression patterns in various tissues and cell types.

With its exceptional performance and versatility, the AIRE-1 Polyclonal Antibody is an indispensable asset for any laboratory or clinical facility involved in autoimmune research and diagnostics. Trust in its reliability and accuracy to advance your understanding of AIRE protein function and its implications in autoimmune disorders.