AK6 Polyclonal Antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF9 encodes one of the smaller subunits of TFIID (TATA-box binding protein associated factor 9) that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. In human, TAF9 and AK6 (GeneID: 102157402) are two distinct genes that share 5' exons. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants.

The AK6 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human AK6 protein. The AK6 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.

The AK6 Polyclonal Antibody is a valuable tool for researchers studying the AK6 protein and its role in various biological processes. This antibody can be used to detect endogenous levels of AK6 protein in various tissues and cell lines. It can also be used to study the expression and localization of AK6 protein in different cell types and tissues.

The AK6 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. This antibody is provided in a liquid form and can be stored at -20°C for long-term use. The AK6 Polyclonal Antibody is available in different sizes and formats to suit the needs of different research applications.

In summary, the AK6 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for studying the AK6 protein in various research applications. This antibody is a valuable tool for researchers studying the role of AK6 in various biological processes and can be used to detect endogenous levels of AK6 protein in different tissues and cell lines.