AKAP 13 Polyclonal Antibody

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.

The AKAP 13 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of AKAP 13 protein in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in research applications.

The AKAP 13 Polyclonal Antibody exhibits a high affinity and specificity towards AKAP 13, a key protein involved in cellular signaling and regulation. It has been produced using advanced techniques and stringent quality control measures to guarantee consistent and reproducible results.

This antibody is suitable for a wide range of experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated in various cell lines and tissues, ensuring its reliability and versatility in different experimental settings.

The AKAP 13 Polyclonal Antibody offers exceptional sensitivity, enabling the detection of low levels of AKAP 13 protein with minimal background interference. Its superior performance allows for accurate quantification and analysis of AKAP 13 expression levels in biological samples.

Furthermore, this antibody has been rigorously characterized to ensure its specificity towards AKAP 13, minimizing the risk of cross-reactivity with other proteins. Its high specificity guarantees reliable and precise results, contributing to the advancement of scientific research.

In summary, the AKAP 13 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of AKAP 13 protein. Its exceptional performance, sensitivity, and specificity make it an invaluable asset for researchers in various fields, including cellular signaling, protein regulation, and disease mechanisms.