AKT mouse Monoclonal Antibody(10D6)

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

The AKT Mouse Monoclonal Antibody (10D6) is a highly specific and reliable tool for the detection and analysis of AKT protein expression. This monoclonal antibody has been meticulously developed and rigorously tested to ensure its exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The AKT Mouse Monoclonal Antibody (10D6) exhibits a high affinity and selectivity towards AKT, a crucial protein involved in multiple cellular processes such as cell survival, proliferation, and metabolism. Its exceptional specificity allows for accurate and precise detection of AKT protein levels, enabling researchers to gain valuable insights into the signaling pathways and mechanisms underlying various diseases and conditions.

This antibody has been manufactured using state-of-the-art techniques and quality-controlled processes to ensure batch-to-batch consistency and reproducibility. Its superior sensitivity and low background noise make it an ideal choice for both qualitative and quantitative analysis of AKT protein expression in various sample types, including cell lysates, tissue sections, and cultured cells.

The AKT Mouse Monoclonal Antibody (10D6) offers exceptional performance and reliability, making it an indispensable tool for researchers and scientists working in the fields of cell biology, cancer research, and drug discovery. With its high specificity, sensitivity, and versatility, this antibody empowers researchers to unravel the intricate molecular mechanisms underlying AKT signaling and its implications in various diseases, ultimately leading to the development of novel therapeutic strategies.

Choose the AKT Mouse Monoclonal Antibody (10D6) for its exceptional quality, reliability, and performance, and unlock new possibilities in your research endeavors.