Akt Polyclonal Antibody

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in AKT1 have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for AKT1.

The Akt Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Akt protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, this antibody enables accurate and precise quantification of Akt protein levels in both research and clinical settings.

The Akt Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other proteins, thus minimizing the risk of false-positive results. Its robustness and reproducibility make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its long shelf life ensures consistent performance over an extended period, reducing the need for frequent reordering.

The Akt Polyclonal Antibody is compatible with various sample types, including cell lysates, tissue extracts, and serum, facilitating its versatility and applicability across different research areas. Its ease of use and compatibility with commonly used detection systems make it an essential tool for researchers and clinicians alike.

Choose the Akt Polyclonal Antibody for its exceptional quality, reliability, and performance. With its high specificity and sensitivity, this antibody will undoubtedly enhance your research outcomes and contribute to a deeper understanding of Akt protein function and regulation.