ALDH2 Polyclonal Antibody

Aldehyde dehydrogenase mitochondrial belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

The ALDH2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of ALDH2 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ALDH2 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing accurate and reliable results.

With its superior sensitivity, this antibody allows for the detection of even low levels of ALDH2 protein, making it an ideal choice for both qualitative and quantitative analysis. Its exceptional specificity ensures minimal background noise, enabling precise and accurate measurements.

The ALDH2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. Its long shelf life and stability make it a cost-effective solution for long-term storage and repeated use.

Whether you are conducting research in the field of alcohol metabolism, drug metabolism, or oxidative stress, the ALDH2 Polyclonal Antibody is an indispensable tool for your studies. Its high quality and reliability make it the preferred choice for scientists and researchers worldwide.

Order your ALDH2 Polyclonal Antibody today and experience the exceptional performance and reliability that this product offers.