ALDH3A1 Polyclonal Antibody

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. ALDH3A1 is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.

The ALDH3A1 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of ALDH3A1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ALDH3A1 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and ELISA.

The ALDH3A1 Polyclonal Antibody is designed to recognize and bind to the ALDH3A1 protein with high affinity and specificity, enabling accurate and reliable detection of this protein in complex biological samples. This antibody has been shown to exhibit minimal cross-reactivity with other ALDH family members, ensuring that the detected signal is specific to ALDH3A1.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using a protein A column. The purified antibody is provided in a liquid format, making it easy to use in a variety of applications. The ALDH3A1 Polyclonal Antibody is suitable for use in both research and diagnostic applications, and has been validated for use in human, mouse, and rat samples.

Overall, the ALDH3A1 Polyclonal Antibody is a reliable and sensitive tool for the detection and quantification of ALDH3A1 protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians studying the role of ALDH3A1 in various physiological and pathological processes.