ALK-1 Polyclonal Antibody

ACVRL1 (activin A receptor like type 1) encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

The ALK-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of ALK-1 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

The ALK-1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards ALK-1, a transmembrane receptor protein involved in angiogenesis and vascular development. It recognizes the extracellular domain of ALK-1, allowing for precise and reliable detection of this protein in tissues and cells.

This antibody has been extensively validated in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It demonstrates excellent performance in both human and animal samples, making it a versatile tool for researchers in various fields, such as cancer biology, cardiovascular research, and developmental biology.

The ALK-1 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. Each batch is rigorously quality-controlled to ensure optimal performance and reproducibility.

With its exceptional sensitivity, specificity, and reliability, the ALK-1 Polyclonal Antibody is an indispensable tool for researchers seeking to investigate the role of ALK-1 in various biological processes. Its high-quality formulation and consistent performance make it a valuable asset in the pursuit of scientific discovery.