Alpha-SMA Polyclonal Antibody

The product (actin, alpha 1, skeletal muscle) encoded by ACTA1 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in ACTA1 cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

The Alpha-SMA Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of alpha-smooth muscle actin (α-SMA) in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards α-SMA.

With its exceptional sensitivity, this polyclonal antibody enables accurate and precise analysis of α-SMA expression levels in tissues and cells. It is suitable for a wide range of applications, including immunohistochemistry, immunofluorescence, and Western blotting.

The Alpha-SMA Polyclonal Antibody exhibits minimal cross-reactivity with other related proteins, ensuring reliable and specific results. Its robust performance allows for the detection of even low levels of α-SMA, making it an ideal choice for both qualitative and quantitative studies.

This antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is available in various sizes to accommodate different experimental needs.

Choose the Alpha-SMA Polyclonal Antibody for its exceptional quality, reliability, and specificity, and unlock new insights into the role of α-SMA in various biological processes.