Amphiphysin I Polyclonal Antibody

AMPH encodes a protein (amphiphysin) associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of AMPH is found on chromosome 11.

The Amphiphysin I Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Amphiphysin I protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Amphiphysin I protein. The resulting polyclonal antibody exhibits high affinity and specificity towards Amphiphysin I protein, making it an ideal tool for various research applications.

The Amphiphysin I Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to detect Amphiphysin I protein in a variety of tissues and cell lines, including brain, kidney, liver, lung, and heart. This antibody is also suitable for use in co-immunoprecipitation and immunocytochemistry experiments.

The Amphiphysin I Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a column containing the immunizing peptide. This ensures that the antibody is highly specific and free from non-specific binding. The antibody is provided in a liquid format, which is ready-to-use for various applications.

In summary, the Amphiphysin I Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Amphiphysin I protein in various biological samples. Its high affinity and specificity make it an essential tool for researchers studying the function and regulation of Amphiphysin I protein in various physiological and pathological processes.