AMPK Beta1 Polyclonal Antibody

Protein kinase AMP-activated non-catalytic subunit beta 1 encoded by PRKAB1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

The KPNA6 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of KPNA6 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards KPNA6.

The KPNA6 Rabbit Polyclonal Antibody exhibits exceptional sensitivity, enabling accurate detection of even low levels of KPNA6 protein. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody offers unparalleled performance, delivering robust and reproducible results across a wide range of experimental conditions. Its exceptional specificity ensures minimal cross-reactivity with other proteins, guaranteeing reliable and accurate data interpretation.

The KPNA6 Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for immediate application in research and diagnostic laboratories. It is provided in a liquid formulation, ensuring ease of use and eliminating the need for time-consuming reconstitution steps.

With its superior quality and performance, the KPNA6 Rabbit Polyclonal Antibody is an indispensable tool for researchers and scientists studying KPNA6 protein function and its involvement in various cellular processes. Trust in this antibody to provide reliable and reproducible results, enabling advancements in the understanding of KPNA6 biology.