AMPK Gamma1/2/3 Polyclonal Antibody

The protein encoded by PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Introducing the AMPK Gamma1/2/3 Polyclonal Antibody, a cutting-edge scientific tool designed to facilitate advanced research in the field of cellular metabolism. This high-quality antibody is meticulously developed using state-of-the-art techniques, ensuring exceptional specificity and sensitivity for the detection of AMPK Gamma1, Gamma2, and Gamma3 isoforms.

With its polyclonal nature, this antibody offers a broad range of applications, making it an invaluable asset for scientists and researchers alike. Its versatility allows for the exploration of various biological processes, including energy homeostasis, glucose metabolism, and autophagy regulation.

The AMPK Gamma1/2/3 Polyclonal Antibody boasts an impressive affinity for its target proteins, enabling precise and reliable detection in a variety of experimental settings. Its exceptional performance is further enhanced by its compatibility with multiple techniques, such as Western blotting, immunohistochemistry, and immunofluorescence.

Crafted with utmost care, this antibody undergoes rigorous quality control measures to ensure consistent and reproducible results. Its exceptional specificity minimizes the risk of cross-reactivity, guaranteeing accurate and reliable data interpretation.

Researchers can confidently rely on the AMPK Gamma1/2/3 Polyclonal Antibody to unlock new insights into the intricate mechanisms governing cellular metabolism. Its exceptional performance, combined with its ease of use, makes it an indispensable tool for those seeking to unravel the complexities of AMPK Gamma isoforms.

Choose the AMPK Gamma1/2/3 Polyclonal Antibody for its unparalleled quality, reliability, and versatility, and embark on a journey of groundbreaking discoveries in the realm of cellular metabolism.