ANKRD30A Polyclonal Antibody

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein.

Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80% of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody‐based therapies in breast cancers.

The ANKRD30A Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The ANKRD30A Polyclonal Antibody is ideal for use in immunohistochemistry, western

blotting, and other applications where high sensitivity and specificity are required. This antibody is designed to detect ANKRD30A protein expression in various tissues and cell types. It is produced using state-of-the-art techniques and is rigorously tested to ensure consistent performance.

The ANKRD30A Polyclonal Antibody is an essential tool for researchers studying ANKRD30A protein expression and function. It is available in various sizes and formats to meet the needs of different research applications. With its high specificity and sensitivity, the ANKRD30A Polyclonal Antibody is a reliable and effective tool for researchers in the field of molecular biology and beyond.