anti- 15 Lipoxygenase 2 antibody

Unlock the power of specificity and precision in your research with our Anti-15 Lipoxygenase 2 Antibody, available in a convenient 100µg size. This high-quality antibody is meticulously designed to target and detect 15 Lipoxygenase 2, an essential enzyme involved in lipid metabolism and inflammation regulation.

Our Anti-15 Lipoxygenase 2 Antibody offers exceptional specificity, ensuring that you can confidently study the role and function of this critical enzyme without cross-reactivity to other proteins. This specificity is vital for elucidating the unique contributions of 15 Lipoxygenase 2 in various cellular pathways and disease mechanisms, including cancer and inflammatory disorders.

With 100µg of this antibody at your disposal, you have an abundant supply to conduct multiple experiments, reducing the need for frequent reorders and ensuring uninterrupted progress in your research. Each batch of our antibody undergoes rigorous quality control measures to guarantee consistent performance and reliability in your experiments.

Whether you are investigating lipid signaling pathways, lipid-derived mediators in inflammation, or the potential therapeutic targets in lipid metabolism disorders, our Anti-15 Lipoxygenase 2 Antibody empowers you to delve deeper into the intricate world of this essential enzyme. Order your supply today and join leading researchers who rely on our high-quality antibodies for their critical work.

Product Name

15 Lipoxygenase 2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.

IMMUNOGEN INFORMATION

Immunogen

arachidonate 15-lipoxygenase, type B

Synonyms

ALOX15B;Arachidonate 15-lipoxygenase B,15-LOX-B,15-LOX-2,Arachidonate 15-lipoxygenase type II,Linoleate 13-lipoxygenase 15-Lob

Observed MW

76 kDa

APPLICATION

Tested Application

ELISA, WB, IHC,IF

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O15296

IMAGES

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab00005(ALOX15B antibody) at dilution of 1:100

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00005(ALOX15B antibody) at dilution of 1:600