anti- 5 Lipoxygenase antibody

Embark on a journey into the world of lipid signaling with our Anti-5 Lipoxygenase Antibody, a high-quality polyclonal antibody hosted by rabbits, available in a convenient 100µg size. 5-Lipoxygenase (5-LOX) is a critical enzyme involved in the metabolism of arachidonic acid, playing a pivotal role in the production of bioactive lipids called leukotrienes.

Our meticulously designed antibody is tailored to specifically target 5-LOX with exceptional specificity and sensitivity. It is an invaluable tool for researchers investigating lipid signaling pathways, inflammation, and the development of therapeutics targeting 5-LOX. Whether you are conducting Western blotting, immunohistochemistry, or lipidomics studies, this antibody empowers you to explore the complex world of lipid metabolism.

The 100µg size ensures you have ample supply for multiple experiments, reducing the need for frequent reorders and ensuring uninterrupted progress in your research. Each batch of our Anti-5 Lipoxygenase Antibody undergoes rigorous quality control measures to guarantee consistent performance and reliability in your experiments. Elevate your lipid signaling research with this versatile and trusted antibody.

Product Name

5 Lipoxygenase antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).

IMMUNOGEN INFORMATION

Immunogen

arachidonate 5-lipoxygenase

Synonyms

5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5

Observed MW

68-78 kDa

APPLICATION

Tested Application

ELISA, IF, WB

Recommended Dilution

WB: 1:200-1:2000; IF: 1:20-1:100

UNIPROT INFORMATION

UniProt ID

P09917

IMAGES

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab00007(ALOX5 Antibody) at dilution of 1:600