anti- AARE antibody

Embark on a journey into the world of gene expression regulation with our Anti-AARE Antibody, available in a 100µg size. AARE, also known as the amino acid response element, is a crucial regulatory element found in the promoters of genes involved in amino acid metabolism and transport. Investigating the function of AARE is essential for understanding the intricate mechanisms governing cellular responses to amino acid availability and their implications in metabolic disorders.

Our meticulously crafted antibody is tailored to specifically target AARE with exceptional specificity and sensitivity, enabling precise detection and quantification in various research applications. Whether you are studying amino acid-responsive gene expression, exploring the role of AARE in metabolic diseases, or investigating its potential as a target for metabolic therapies, this antibody is an invaluable tool for your research endeavors.

Product Name

AARE antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

APH,(APEH, acylpeptide hydrolase), which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. A range of molecular masses have been reported for APH by previous investigators, including 80 kD, 75 kD and 69 kD. This antibody can recognize at least 2 isoforms of APH.

IMMUNOGEN INFORMATION

Immunogen

N-acylaminoacyl-peptide hydrolase

Synonyms

AARE, ACPH, Acyl peptide hydrolase, Acylaminoacyl peptidase, APEH, APH, D3F15S2, D3S48E, DNF15S2, OPH, Oxidized protein hydrolase

Observed MW

81 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P13798

IMAGES

Immunohistochemistry of paraffin-embedded human liver using FNab00021(APEH antibody) at dilution of 1:100

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00021(APEH antibody) at dilution of 1:1000