anti- ACADVL antibody

Illuminate the role of ACADVL in fatty acid oxidation with our Anti-ACADVL Antibody. With a substantial 100µg supply, this antibody empowers you to explore ACADVL and its pivotal role in mitochondrial fatty acid metabolism.

ACADVL, also known as very long-chain acyl-CoA dehydrogenase, is a key enzyme in the breakdown of long-chain fatty acids within mitochondria. Our antibody is precision-engineered to specifically target ACADVL with remarkable precision and sensitivity. Thoroughly validated, it ensures consistent and dependable results, instilling confidence in your exploration of fatty acid oxidation pathways.

Produced using state-of-the-art techniques, this antibody is sourced from rabbit hosts, featuring a polyclonal clonality that broadens its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunoprecipitation, and immunofluorescence assays.

Whether you're unraveling fatty acid catabolism mechanisms, studying mitochondrial bioenergetics, or exploring diseases related to ACADVL deficiencies, our Anti-ACADVL Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling pioneering discoveries and contributions to metabolic research.

Elevate your research with the precision and reliability of our Anti-ACADVL Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACADVL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.

IMMUNOGEN INFORMATION

Immunogen

acyl-Coenzyme A dehydrogenase, very long chain

Synonyms

ACAD6, ACADVL, LCACD, VLCAD

Observed MW

48 kDa,68-73 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P49748

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer using FNab00068(ACADVL antibody) at dilution of 1:50

Various lysates were subjected to SDS PAGE followed by western blot with FNab00068(ACADVL antibody) at dilution of 1:1000