anti- ACAT1 antibody

Explore the role of ACAT1 in cellular lipid homeostasis with our Anti-ACAT1 Antibody. This invaluable tool, available in a substantial 100µg size, empowers you to delve into ACAT1 and its pivotal role in cholesterol metabolism and lipid storage.

ACAT1, also known as Acyl-CoA:cholesterol acyltransferase 1, is a key enzyme involved in esterifying cholesterol for storage in lipid droplets. Our antibody is meticulously crafted to specifically target ACAT1 with remarkable sensitivity. Thoroughly validated, it ensures consistent and dependable results, instilling confidence in your exploration of lipid metabolic pathways.

Utilizing state-of-the-art techniques, this antibody is sourced from rabbit hosts, featuring a polyclonal clonality that broadens its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunoprecipitation, and immunofluorescence assays.

Whether you're investigating cholesterol esterification mechanisms, studying lipid droplet biogenesis, or exploring diseases related to ACAT1 dysregulation, our Anti-ACAT1 Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling pioneering discoveries and contributions to lipid research.

Empower your research with the precision and reliability of our Anti-ACAT1 Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACAT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

IMMUNOGEN INFORMATION

Immunogen

acetyl-Coenzyme A acetyltransferase 1

Synonyms

ACAT, ACAT1, Acetoacetyl CoA thiolase, MAT, T2, THIL

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P24752

IMAGES

Immunohistochemistry of paraffin-embedded human liver using FNab00072(ACAT1 antibody) at dilution of 1:100

human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab00072(ACAT1 antibody) at dilution of 1:1000