anti- ACC1 antibody

Explore the intricate world of fatty acid biosynthesis with our Anti-ACC1 Antibody. With a generous 100µg supply, this antibody empowers you to delve into ACC1 and its pivotal role in the synthesis of long-chain fatty acids.

ACC1, also known as acetyl-CoA carboxylase 1, is a key enzyme in fatty acid biosynthesis, catalyzing the conversion of acetyl-CoA into malonyl-CoA, a crucial precursor in fatty acid synthesis. Our antibody is meticulously crafted to specifically target ACC1 with remarkable precision and sensitivity. Rigorously validated, it ensures consistent and dependable results, instilling confidence in your exploration of lipid metabolic pathways.

Utilizing state-of-the-art techniques, this antibody is sourced from rabbit hosts, featuring a polyclonal clonality that broadens its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunohistochemistry, and immunofluorescence assays.

Whether you're unraveling fatty acid biosynthesis mechanisms, studying lipid metabolism, or exploring diseases related to ACC1 dysregulation, our Anti-ACC1 Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling groundbreaking discoveries and contributions to metabolic research.

Empower your research with the precision and reliability of our Anti-ACC1 Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

IMMUNOGEN INFORMATION

Immunogen

acetyl-Coenzyme A carboxylase alpha

Synonyms

ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1

Observed MW

270 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13085

IMAGES

Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab00077(ACC1 antibody) at dilution of 1:50

Immunofluorescent analysis of HeLa cells using FNab00077(ACC1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACC1 antibody) at dilution of 1:500