anti- ACVR1C antibody

Uncover the intricacies of signaling pathways with our Anti-ACVR1C Antibody. This indispensable research tool, available in a generous 100µg size, provides you with the precision and reliability needed to explore ACVR1C and its involvement in cellular signaling.

ACVR1C, also known as activin receptor type-1C, is a member of the TGF-β receptor family, playing a role in various signaling cascades. It is implicated in multiple cellular processes, including cell differentiation and tissue development. Our antibody is precision-engineered to specifically target ACVR1C with remarkable sensitivity. Thoroughly validated, it ensures consistent and dependable results, empowering you to delve into the intricacies of signaling pathways.

Utilizing state-of-the-art techniques, this antibody is sourced from rabbit hosts, featuring a polyclonal clonality that broadens its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunoprecipitation, and immunofluorescence assays.

Whether you're unraveling the roles of ACVR1C in cell differentiation, studying tissue development, or investigating ACVR1C-related conditions, our Anti-ACVR1C Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling groundbreaking discoveries and contributions to cellular signaling research.

Empower your research with the precision and reliability of our Anti-ACVR1C Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACVR1C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

IMMUNOGEN INFORMATION

Immunogen

activin A receptor, type IC

Synonyms

ACVR1C, Activin receptor type 1C, Activin receptor type IC, ACVRLK7, ALK 7

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

Q8NER5

IMAGES

Immunohistochemistry of paraffin-embedded human stomach using FNab00130(ACVR1C antibody) at dilution of 1:100

SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00130(ACVR1C antibody) at dilution of 1:1000