anti- ACVRL1 antibody

Unveil the secrets of vascular development with our Anti-ACVRL1 Antibody. With a substantial 100µg supply, this antibody empowers you to explore ACVRL1 and its pivotal role in the formation and maintenance of blood vessels.

ACVRL1, also known as activin receptor-like kinase 1, is a crucial component of the TGF-β signaling pathway, playing a key role in angiogenesis and vascular development. Our antibody is meticulously crafted to specifically target ACVRL1 with remarkable precision and sensitivity. Rigorously validated, it ensures consistent and dependable results, instilling confidence in your exploration of vascular biology.

Produced using cutting-edge techniques, this antibody is sourced from rabbit hosts, offering a polyclonal clonality that broadens its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunoprecipitation, and immunofluorescence assays.

Whether you're unraveling the mechanisms of angiogenesis, studying vascular diseases, or investigating ACVRL1-related conditions, our Anti-ACVRL1 Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling groundbreaking discoveries and contributions to vascular biology research.

Empower your research with the precision and reliability of our Anti-ACVRL1 Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACVRL1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

IMMUNOGEN INFORMATION

Immunogen

activin A receptor type II-like 1

Synonyms

Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I

Observed MW

56 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC, IP

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

P37023

IMAGES

Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab00131(ACVRL1 Antibody) at dilution of 1:200

IP Result of anti-ACVRL1 (IP:FNab00131, 4ug; Detection:FNab00131 1:300) with Jurkat cells lysate 2400ug.

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00131(ACVRL1 antibody) at dilution of 1:400