anti- ADAR1 antibody

Uncover the functions of ADAR1 with precision using our Anti-ADAR1 Antibody, available in a 100µg size. ADAR1, also known as Adenosine Deaminase, RNA-Specific, 1, is a key enzyme involved in RNA editing by catalyzing the conversion of adenosine to inosine in RNA molecules. Understanding its functions demands a specific and reliable antibody, and our product delivers just that.

Our Anti-ADAR1 Antibody offers exceptional sensitivity and specificity, allowing you to explore ADAR1's roles with confidence. Whether you're conducting Western blotting experiments, immunoprecipitation assays, or immunofluorescence studies, this versatile antibody adapts seamlessly to your research needs. Its reputation for reliability ensures consistent and reproducible results, empowering you to advance your scientific inquiries.

Join researchers worldwide who trust our antibodies to drive their discoveries. Order your Anti-ADAR1 Antibody today and embark on a journey to unravel the intricacies of ADAR1's functions, revolutionizing your research outcomes.

Product Name

ADAR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

IMMUNOGEN INFORMATION

Immunogen

adenosine deaminase, RNA-specific

Synonyms

ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136

Observed MW

110 kDa

APPLICATION

Tested Application

ELISA, IHC, IF, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IP: 1:200-1:1000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P55265

IMAGES

Immunohistochemistry of paraffin-embedded human gliomas using FNab00150(ADAR1 antibody) at dilution of 1:50

IP Result of anti-ADAR1 (IP:FNab00150, 4ug; Detection:FNab00150 1:500) with Y79 cells lysate 3000ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150(ADAR1 Antibody) at dilution of 1:1000