anti- ADCY6 antibody

Delve into the intricate world of cellular signaling and second messenger systems with our Anti-ADCY6 Antibody, available in a 100µg size. Adenylate cyclase 6 (ADCY6), also known as adenylyl cyclase type VI, is a pivotal enzyme in intracellular signaling pathways, responsible for converting adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). Understanding its functions is essential for unraveling the complexities of cAMP signaling and its profound impacts on cellular processes.

Our Anti-ADCY6 Antibody offers exceptional sensitivity and specificity, enabling you to investigate the roles of ADCY6 with precision. Whether you're conducting Western blotting experiments, immunoprecipitation assays, or immunofluorescence studies, this versatile antibody seamlessly adapts to your research needs. Its reputation for reliability ensures consistent and reproducible results, empowering you to advance your scientific inquiries with confidence.

cAMP signaling is a fundamental mechanism with far-reaching implications in cellular physiology, neuroscience, and pharmacology. Researchers exploring neuronal signaling, hormonal regulation, or drug development targeting cAMP pathways can trust our antibody as an invaluable tool.

Join researchers worldwide who rely on our antibodies to drive their discoveries. Order your Anti-ADCY6 Antibody today and embark on a journey to unlock the secrets of ADCY6, revolutionizing your research outcomes and contributing to advancements in our understanding of cellular communication, signal transduction, and the intricate world of adenylate cyclases. Explore the intricacies of cellular signaling with precision and confidence, armed with this powerful tool in your laboratory arsenal.

Product Name

ADCY6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).

IMMUNOGEN INFORMATION

Immunogen

adenylate cyclase 6

Synonyms

AC6, ADCY6, adenylate cyclase 6, Adenylate cyclase type 6, Adenylate cyclase type VI, Adenylyl cyclase 6, ATP pyrophosphate lyase 6, DKFZp779F075, KIAA0422

Observed MW

131 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

O43306

IMAGES

IP Result of anti-ADCY6 (IP:FNab00157, 4ug; Detection:FNab00157 1:300) with mouse brain tissue lysate 4000ug.

human brain tissue were subjected to SDS PAGE followed by western blot with FNab00157(ADCY6 antibody) at dilution of 1:200