anti- AEG-1/MTDH-Specific antibody

Introducing our highly specialized Anti-AEG-1/MTDH-Specific Antibody, now available in a convenient 100µg size, poised to revolutionize your research in the realm of oncology and cancer biology.

The Anti-AEG-1/MTDH-Specific Antibody is meticulously crafted to meet the exacting standards of the scientific community. AEG-1 (Astrocyte Elevated Gene-1), also known as MTDH (Metadherin), plays a pivotal role in promoting cancer metastasis and progression, making it a critical target in cancer research. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for various applications, from immunohistochemistry to tumor xenograft studies and beyond.

What truly sets our Anti-AEG-1/MTDH-Specific Antibody apart is its unrivaled performance. It has undergone rigorous testing and validation to ensure reliable and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between economy and usability. You'll have an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered with user-friendliness in mind, our Anti-AEG-1/MTDH-Specific Antibody is suitable for researchers at all experience levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AEG-1/MTDH-Specific Antibody at your disposal. Step into the forefront of scientific discovery in oncology and cancer biology with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you delve into the intricacies of AEG-1/MTDH's roles in cancer metastasis and progression.

Product Name

AEG-1/MTDH-Specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.

IMMUNOGEN INFORMATION

Immunogen

metadherin

Synonyms

3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC

Observed MW

64 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q86UE4

IMAGES

Immunohistochemistry of paraffin-embedded mouse brain using FNab00189(AEG-1 antibody) at dilution of 1:200

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00189(AEG-1 antibody) at dilution of 1:1000