FineTest
SKU(재고 관리 코드):FNab00196
anti- AFF4 antibody
anti- AFF4 antibody
Discover the power of our Anti-AFF4 Polyclonal Antibody, now available in a convenient 100µg size, designed to revolutionize your research in the dynamic field of transcriptional regulation and gene expression.
The Anti-AFF4 Antibody is meticulously crafted to meet the rigorous demands of the scientific community. AFF4 (AF4/FMR2 Family Member 4) is a pivotal player in transcriptional elongation and the formation of the super elongation complex (SEC), making it a central focus in studies of gene regulation. Our polyclonal antibody offers exceptional specificity and sensitivity, rendering it an ideal choice for various applications, from chromatin immunoprecipitation to RNA polymerase II activity assays and more.
What truly sets our Anti-AFF4 Polyclonal Antibody apart is its exceptional performance. It has undergone rigorous testing and validation to ensure consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.
With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.
Engineered with user-friendliness in mind, our Anti-AFF4 Polyclonal Antibody is suitable for researchers at all levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.
Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AFF4 Polyclonal Antibody at your fingertips. Step into the forefront of scientific discovery in transcriptional regulation and gene expression with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you unravel the complexities of AFF4's roles in controlling gene expression and cellular function.
Explore the world of gene regulation with precision and reliability, and unlock the secrets of transcriptional elongation with the Anti-AFF4 Polyclonal Antibody. Elevate your research to new heights and be part of groundbreaking advancements in gene expression studies.
Product Name
AFF4 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.
IMMUNOGEN INFORMATION
Immunogen
AF4/FMR2 family, member 4
Synonyms
AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31
Observed MW
150 kDa
APPLICATION
Tested Application
ELISA, WB, IHC
Recommended Dilution
WB: 1:200-1:2000
UNIPROT INFORMATION
UniProt ID
IMAGES
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00196(AFF4 Antibody) at dilution of 1:600
