anti- AGAP2 antibody

Unveiling our advanced Anti-AGAP2 Antibody, available in a convenient 100µg size, poised to revolutionize your research in the fields of cell biology and intracellular trafficking.

The Anti-AGAP2 Antibody is meticulously crafted to meet the exacting standards of the scientific community. AGAP2 (Arf-GAP with GTPase, ANK repeat, and PH domain-containing protein 2) plays a pivotal role in membrane dynamics and vesicle trafficking, making it a central focus in cellular studies. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for a wide range of applications, from immunofluorescence to co-immunoprecipitation and beyond.

What truly sets our Anti-AGAP2 Antibody apart is its outstanding performance. It has undergone rigorous testing and validation to ensure consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and usability. You'll have an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AGAP2 Antibody is suitable for researchers at all experience levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AGAP2 Antibody at your fingertips. Step into the forefront of scientific discovery in cell biology with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the complexities of intracellular trafficking with the Anti-AGAP2 Antibody.

Product Name

AGAP2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

GTPase-activating protein(GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1(GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1(AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.

IMMUNOGEN INFORMATION

Immunogen

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Synonyms

AGAP 2, AGAP2, Centaurin gamma 1, CENTG1, Cnt g1, FLJ16430, GGAP2, KIAA0167, PIKE

Observed MW

125 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q99490

IMAGES

Immunohistochemistry of paraffin-embedded human gliomas using FNab00205(AGAP2 antibody) at dilution of 1:100

human brain tissue were subjected to SDS PAGE followed by western blot with FNab00205(AGAP2 antibody) at dilution of 1:500