anti- AGS3 antibody

Unlock the potential of your research with our cutting-edge Anti-AGS3 Antibody, now available in a convenient 100µg size, meticulously crafted to advance your studies in the intricate field of G-protein signaling and cellular regulation.

The Anti-AGS3 Antibody is designed to meet the exacting standards of the scientific community. AGS3 (Activator of G-protein Signaling 3), also known as G-protein Signaling Modulator 1 (GPSM1), is a crucial regulator of G-protein-coupled receptor (GPCR) signaling pathways, making it a central focus in studies of cellular signal transduction. Our antibody offers exceptional specificity and sensitivity, rendering it an ideal choice for various applications, from immunoprecipitation to immunofluorescence and more.

What truly sets our Anti-AGS3 Antibody apart is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AGS3 Antibody is suitable for researchers at all levels, from novices to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AGS3 Antibody at your fingertips. Step into the forefront of scientific discovery in GPCR signaling and cellular regulation with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AGS3's roles in cellular signaling and receptor modulation.

Product Name

AGS3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

IMMUNOGEN INFORMATION

Immunogen

G-protein signaling modulator 1(AGS3-like, C. elegans)

Synonyms

AGS3, DKFZp727I051, GPSM1

Observed MW

72 kDa

APPLICATION

Tested Application

ELISA, IHC, IF, WB

Recommended Dilution

WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q86YR5

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab00221(AGS3 antibody) at dilution of 1:50

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(AGS3 antibody) at dilution of 1:600