anti- AIF antibody

Elevate your research in mitochondrial biology and programmed cell death with our state-of-the-art Anti-AIF Antibody, now available in a convenient 100µg size.

The Anti-AIF Antibody, also known as Apoptosis-Inducing Factor, is meticulously crafted to meet the demanding standards of the scientific community. AIF is a pivotal protein involved in mitochondrial function and programmed cell death, making it a central focus in studies of cell biology and neurodegenerative diseases. Our antibody offers exceptional specificity and sensitivity, rendering it an ideal choice for various applications, from immunohistochemistry to mitochondrial isolation assays and more.

What truly sets our Anti-AIF Antibody apart is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AIF Antibody is suitable for researchers at all levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AIF Antibody at your fingertips. Step into the forefront of scientific discovery in mitochondrial biology and apoptosis with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AIF's roles in maintaining mitochondrial integrity and orchestrating programmed cell death.

Product Name

AIF antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.

IMMUNOGEN INFORMATION

Immunogen

apoptosis-inducing factor, mitochondrion-associated, 1

Synonyms

AIF, AIFM1, PDCD8

Observed MW

67 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O95831

IMAGES