anti- AIM2 antibody

Advance your research in innate immunity and inflammasome activation with our advanced Anti-AIM2 Antibody, now available in a convenient 100µg size.

The Anti-AIM2 Antibody, also known as Absent in Melanoma 2, is meticulously crafted to meet the exacting standards of the scientific community. AIM2 is a critical protein involved in sensing cytoplasmic DNA and initiating inflammatory responses, making it a central focus in studies of innate immunity and autoinflammatory diseases. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for various applications, from immunoprecipitation to flow cytometry and more.

What truly sets our Anti-AIM2 Antibody apart is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and usability. You'll have an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered with user-friendliness in mind, our Anti-AIM2 Antibody is suitable for researchers at all levels, from novices to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AIM2 Antibody at your fingertips. Step into the forefront of scientific discovery in innate immune responses and inflammasome biology with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AIM2's roles in host defense and autoinflammatory disorders.

Product Name

AIM2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8(By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

IMMUNOGEN INFORMATION

Immunogen

absent in melanoma 2

Synonyms

Absent in melanoma 2, AIM2, PYHIN4

Observed MW

38-45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-200

UNIPROT INFORMATION

UniProt ID

O14862

IMAGES