anti- Ajuba antibody

Embark on a journey into the realm of cell adhesion and signaling with our state-of-the-art Anti-Ajuba Antibody, now available in a convenient 100µg size.

The Anti-Ajuba Antibody is meticulously crafted to meet the rigorous demands of the scientific community. Ajuba is a critical protein involved in the regulation of cell-cell adhesion and cytoskeletal dynamics, making it a central focus in studies of cell biology and tissue development. Our antibody offers exceptional specificity and sensitivity, rendering it an ideal choice for various applications, from immunofluorescence to protein-protein interaction studies and more.

What truly sets our Anti-Ajuba Antibody apart is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-Ajuba Antibody is suitable for researchers at all levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-Ajuba Antibody at your fingertips. Step into the forefront of scientific discovery in cell adhesion and tissue morphogenesis with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of Ajuba's roles in cellular dynamics and tissue architecture.

Product Name

Ajuba antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an important role in regulation of the kinase activity of AURKA for mitotic commitment. Also a component of the IL-1 signaling pathway modulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex. Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Positively regulates microRNA(miRNA)-mediated gene silencing. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1.

IMMUNOGEN INFORMATION

Immunogen

jub, ajuba homolog

Synonyms

Ajuba, JUB, Protein ajuba

Observed MW

57 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-200

UNIPROT INFORMATION

UniProt ID

Q96IF1

IMAGES