anti- AKR1C3 antibody

Delve into the complex world of steroid hormone metabolism and aldo-keto reductases with our state-of-the-art Anti-AKR1C3 Antibody, now available in a convenient 100µg size.

The Anti-AKR1C3 Antibody, also known as Aldo-Keto Reductase Family 1 Member C3, is meticulously designed to meet the exacting standards of the scientific community. AKR1C3 plays a crucial role in the biosynthesis and metabolism of steroid hormones, making it a central focus in endocrinology and cancer research. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for applications such as enzyme assays, hormone metabolism studies, and more.

What truly distinguishes our Anti-AKR1C3 Antibody is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AKR1C3 Antibody is suitable for researchers at all levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AKR1C3 Antibody at your disposal. Step into the forefront of scientific discovery in steroid hormone metabolism and hormone-related diseases with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AKR1C3's roles in hormone biosynthesis and cancer progression.

Product Name

AKR1C3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)

Synonyms

17 beta HSD 5, 3 alpha HSD type 2, 3 alpha HSD type II, brain, AKR1C3, DD 3, DD3, DDX, Dihydrodiol dehydrogenase 3, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, Prostaglandin F synthase

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P42330

IMAGES