anti- AKT1 antibody

Welcome to a world of scientific discovery with our Anti-AKT1 Antibody, available in a convenient 100µg size. This antibody is your essential partner in unraveling the intricacies of the Akt signaling pathway.

The Anti-AKT1 Antibody offers exceptional specificity and sensitivity, making it an ideal choice for a variety of applications, including Western blotting and immunohistochemistry. Its precision in targeting Akt1 ensures reliable and reproducible results in your experiments.

What distinguishes our Anti-AKT1 Antibody is its exceptional performance. It has undergone rigorous testing and validation to ensure that it consistently delivers high-quality results, reducing experimental variability and optimizing resource utilization.

With a 100µg size, this product provides an ideal balance between cost-effectiveness and usability, offering sufficient antibody for multiple experiments while minimizing wastage.

Whether you're a seasoned researcher or just starting in the field, our Anti-AKT1 Antibody is user-friendly and seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your work.

Empower your research with confidence, knowing you have the support of a meticulously crafted Anti-AKT1 Antibody. Step into the forefront of scientific discovery in cell signaling and cancer biology with this essential tool and contribute to groundbreaking insights in the field.

Product Name

AKT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

v-akt murine thymoma viral oncogene homolog 1

Synonyms

AKT, AKT1, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P31749

IMAGES