anti- AKT3 antibody

Dive into the intricate world of the Akt signaling pathway with our advanced Anti-AKT3 Antibody, now available in a convenient 100µg size.

The Anti-AKT3 Antibody, a key player in the Akt kinase family, is meticulously designed to meet the exacting standards of the scientific community. AKT3 plays a pivotal role in regulating cell growth, metabolism, and survival, making it a central focus in cancer research and molecular biology. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for applications such as Western blotting, immunohistochemistry, and more.

What truly distinguishes our Anti-AKT3 Antibody is its impeccable performance. Rigorously tested and validated, it ensures reliable and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product provides an ideal balance between economy and usability, offering sufficient antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AKT3 Antibody is suitable for researchers at all levels, from novices to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AKT3 Antibody at your fingertips. Step into the forefront of scientific discovery in cell signaling and cancer biology with this essential tool and contribute to groundbreaking insights in the field.

Product Name

AKT3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

AKT3 is one of 3 closely related serine/threonine-protein kinases(AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.

IMMUNOGEN INFORMATION

Immunogen

v-akt murine thymoma viral oncogene homolog 3(protein kinase B, gamma)

Synonyms

AKT3, DKFZp434N0250, PKB GAMMA, PKBG, PRKBG, Protein kinase Akt 3, Protein kinase B gamma, RAC gamma, RAC PK gamma, STK 2

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9Y243

IMAGES