anti- ALDH2 antibody

Embark on a journey into the realm of aldehyde dehydrogenase 2 (ALDH2) with our highly specialized Anti-ALDH2 Antibody, now available in a convenient 100µg size.

ALDH2 is a crucial enzyme involved in the detoxification of ethanol-derived acetaldehyde and is associated with alcohol metabolism and related diseases. Our antibody is meticulously designed to provide unparalleled specificity and sensitivity, making it an ideal choice for various applications, from Western blotting to immunohistochemistry and beyond.

What truly sets our Anti-ALDH2 Antibody apart is its exceptional performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a generous 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage. This aligns with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-ALDH2 Antibody is suitable for researchers at all levels, from novices to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-ALDH2 Antibody. Step into the forefront of scientific discovery in alcohol metabolism and related fields with this essential tool and contribute to groundbreaking insights in the field.

Product Name

ALDH2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

IMMUNOGEN INFORMATION

Immunogen

aldehyde dehydrogenase 2 family (mitochondrial)

Synonyms

ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM

Observed MW

53 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P05091

IMAGES