anti- ALK,CD246 antibody

Step into the world of ALK (Anaplastic Lymphoma Kinase) with our specialized Anti-ALK, CD246 Antibody, now available in a convenient 100µg size. ALK is a receptor tyrosine kinase that plays a significant role in cell growth and development. Our meticulously crafted antibody offers exceptional specificity and sensitivity, making it the perfect choice for a wide range of applications, from immunohistochemistry to Western blotting.

What truly distinguishes our Anti-ALK, CD246 Antibody is its outstanding performance. It has undergone rigorous testing and validation to ensure consistent and reproducible results, effectively reducing experimental variability and saving valuable time and resources.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-ALK, CD246 Antibody is suitable for researchers at all levels, whether you're a newcomer or an experienced scientist. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Unlock the full potential of your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-ALK, CD246 Antibody. Explore the intricate world of cell signaling and contribute to groundbreaking insights in the field.

Product Name

ALK,CD246 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ALK, also named as CD246, is a receptor tyrosine kinase(RTK) that belongs to the protein kinase superfamily. ALK is usually found in the nervous system and appears to play an important role in the normal development and function of the nervous system. ALK was originally identified as part of the NPM(Nucleophosmin)-ALK oncogenic fusion protein, resulting from the(2;5)(p23;q35) translocation that is frequently associated with anaplastic large-cell lymphoma(ALCL). The EML4(echinoderm microtubule-associated protein-like 4)-ALK fusion protein have been described in non-small-cell lung cancer(NSCLC), this transforming fusion kinase is a promising candidate for a therapeutic target as well as for a diagnostic molecular marker in NSCLC(PMID: 17625570).

IMMUNOGEN INFORMATION

Immunogen

anaplastic lymphoma receptor tyrosine kinase

Synonyms

ALK, ALK tyrosine kinase receptor, ALK,CD246, Anaplastic lymphoma kinase, CD246, TFG/ALK

Observed MW

176 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UM73

IMAGES