anti- ALKBH7 antibody

Embark on a journey into the realm of RNA modification with our specialized Anti-ALKBH7 Antibody, now available in a convenient 100µg size. ALKBH7 is a pivotal enzyme involved in the oxidative demethylation of N6-methyladenosine (m6A) in RNA, a critical process that regulates RNA stability and function. Our meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for various applications, from RNA epigenetics research to immunofluorescence assays.

What truly sets our Anti-ALKBH7 Antibody apart is its outstanding performance. It has undergone rigorous testing and validation to ensure consistent and reproducible results, effectively reducing experimental variability and saving valuable time and resources.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-ALKBH7 Antibody is suitable for researchers at all levels, whether you're a novice or an experienced scientist. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Unlock the full potential of your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-ALKBH7 Antibody. Dive into the intricate world of RNA epigenetics and contribute to groundbreaking insights in the field.

Product Name

ALKBH7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).

IMMUNOGEN INFORMATION

Immunogen

alkB, alkylation repair homolog 7(E. coli)

Synonyms

ABH7, ALKBH7, SPATA11, UNQ6002

Observed MW

25 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9BT30

IMAGES