anti- Alpha-2-macroglobulin antibody

Explore the world of protease inhibition and immune modulation with our specialized Monoclonal Anti-Alpha-2-Macroglobulin Antibody, now available in a convenient 100µg size. Alpha-2-macroglobulin is a versatile glycoprotein known for its role as a broad-spectrum protease inhibitor and its involvement in immune responses. Our meticulously crafted monoclonal antibody offers exceptional specificity and sensitivity, making it an ideal choice for various research applications, from enzyme assays to immunohistochemistry.

What truly distinguishes our Monoclonal Anti-Alpha-2-Macroglobulin Antibody is its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Monoclonal Anti-Alpha-2-Macroglobulin Antibody is suitable for researchers of all experience levels, from newcomers to seasoned scientists. It seamlessly integrates into various laboratory techniques, enhancing the accuracy and dependability of your experiments.

Contribute to a deeper understanding of protease regulation and immune function with confidence, knowing you have the support of a high-quality, meticulously crafted Monoclonal Anti-Alpha-2-Macroglobulin Antibody. Drive advances in immunology and protease biology and be part of groundbreaking discoveries in host defense mechanisms.

Product Name

Alpha-2-macroglobulin antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.

IMMUNOGEN INFORMATION

Immunogen

alpha-2-macroglobulin

Synonyms

A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, α-2M

Observed MW

185 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:50-1:500; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P01023

IMAGES

 

Immunohistochemistry of paraffin-embedded human liver slide using FNab00341(A2M Antibody) at dilution of 1:50

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00341(A2M antibody) at dilution of 1:1000