anti- alpha Actinin antibody

Delve into the dynamics of the actin cytoskeleton with our specialized Anti-Alpha Actinin Antibody, now available in a convenient 100µg size. Alpha actinin is a critical protein involved in actin filament cross-linking and anchoring. Our meticulously crafted antibody offers exceptional specificity and sensitivity, making it the perfect choice for a wide range of applications, from cell biology research to immunohistochemistry.

What truly sets our Anti-Alpha Actinin Antibody apart is its outstanding performance. It has undergone rigorous testing and validation to ensure consistent and reproducible results, effectively reducing experimental variability and saving valuable time and resources.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-Alpha Actinin Antibody is suitable for researchers at all levels, whether you're a newcomer or an experienced scientist. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Unlock the full potential of your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-Alpha Actinin Antibody. Dive into the complex world of cytoskeletal regulation and contribute to groundbreaking insights in the field.

Product Name

alpha Actinin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

actinin, alpha 1

Synonyms

actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1

Observed MW

110 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P12814

IMAGES