anti- Alpha B Crystallin antibody

Embark on a journey into the fascinating world of small heat shock proteins with our specialized Anti-Alpha B Crystallin Antibody, now available in a convenient 100µg size. Alpha B crystallin, also known as HspB5, is a member of the small heat shock protein family, implicated in various cellular processes, including protein folding and cytoprotection. Our meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for a wide range of research applications, from immunofluorescence to Western blotting.

What truly distinguishes our Anti-Alpha B Crystallin Antibody is its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-Alpha B Crystallin Antibody is suitable for researchers of all experience levels, from newcomers to seasoned scientists. It seamlessly integrates into various laboratory techniques, enhancing the accuracy and dependability of your experiments.

Contribute to a deeper understanding of small heat shock proteins and their role in cellular homeostasis with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-Alpha B Crystallin Antibody. Advance your research and be part of groundbreaking discoveries in cell biology.

Product Name

Alpha B Crystallin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.

IMMUNOGEN INFORMATION

Immunogen

crystallin, alpha B

Synonyms

Alpha B Crystallin, Alpha crystallin B chain, Alpha(B) crystallin, CRYA2, CRYAB, crystallin, alpha B, CTPP2, Heat shock protein beta 5, HSPB5, Rosenthal fiber component

Observed MW

20 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P02511

IMAGES