anti- AMPK beta 1 antibody

Enter the realm of cellular energy regulation with our specialized Anti-AMPK Beta 1 Antibody, now available in a 100µg size. AMP-activated protein kinase (AMPK) is a central player in cellular energy sensing, making it a pivotal target for researchers investigating metabolic disorders and cellular signaling pathways.

Our meticulously crafted Anti-AMPK Beta 1 Antibody offers exceptional specificity and sensitivity, making it a versatile tool for various research applications, from Western blotting to immunoprecipitation. It has undergone stringent validation to ensure consistent and reproducible results, reducing experimental variability and enhancing research efficiency.

With 100µg of high-quality antibody, this product provides ample material for multiple experiments, ensuring cost-effectiveness without compromising on quality. Its user-friendly design caters to researchers of all experience levels, facilitating precise and reliable experiments across diverse laboratory techniques.

Contribute to a deeper understanding of metabolic disorders, cellular signaling, and energy metabolism with confidence, supported by our high-quality Anti-AMPK Beta 1 Antibody. Drive advancements in molecular and cellular biology research and be part of groundbreaking discoveries in cellular energy regulation.

Product Name

AMPK beta 1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

IMMUNOGEN INFORMATION

Immunogen

protein kinase, AMP-activated, beta 1 non-catalytic subunit

Synonyms

AMPK, AMPK beta 1, AMPK subunit beta 1, AMPKb, HAMPKb, PRKAB1

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9Y478

IMAGES