anti- Angiotensinogen antibody

Explore the intricate world of blood pressure regulation and cardiovascular health with our Anti-Angiotensinogen Antibody, now available in a convenient 100µg size. Angiotensinogen, the precursor of angiotensin, plays a pivotal role in the renin-angiotensin-aldosterone system, making it a critical target for cardiovascular research.

Our Anti-Angiotensinogen Antibody is rigorously designed to provide exceptional specificity and sensitivity for various research applications, from immunohistochemistry to ELISA assays. Extensive validation ensures consistent and reproducible results, minimizing experimental variability and enhancing research efficiency.

With 100µg of high-quality antibody, this product offers ample material for multiple experiments, maintaining cost-effectiveness without compromising quality. Its user-friendly design accommodates researchers of all experience levels, enabling precise and reliable experiments across diverse laboratory techniques.

Contribute to advancing our understanding of blood pressure regulation, hypertension, and cardiovascular diseases with confidence, supported by our high-quality Anti-Angiotensinogen Antibody. Join the forefront of cardiovascular research and contribute to groundbreaking discoveries in cardiovascular health.

Product Name

Angiotensinogen antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

IMMUNOGEN INFORMATION

Immunogen

angiotensinogen(serpin peptidase inhibitor, clade A, member 8)

Synonyms

AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, FLJ92595, FLJ97926, Serpin A8, SERPINA8

Observed MW

53 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P01019

IMAGES